I gave TreeMix a try on samples of 30 individuals from all the HapMap-3 populations. The following was done with ~260k SNPs and default parameters. I specified -m 4, that is, I allowed for 4 migration events, and specified YRI as the outgroup to produce this result.
I'll have to explore the intricacies of the visualization parameters a little further, and see how to extract some raw numbers from the output files, but overall, the results seem quite reasonable:
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If I'm interpreting the figure correctly, there seems to be:
This seems like a neat tool for exploring human (and canid ;-) population history.![]()
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I'll have to explore the intricacies of the visualization parameters a little further, and see how to extract some raw numbers from the output files, but overall, the results seem quite reasonable:
- progressively more drift (left-to-right) from Africa to Mexico (the only Native American-admixed population)
- Mexicans are related to East Asian populations (CHD, CHB and especially JPT) and have a strong migration edge from a West Eurasian source (related to CEU and TSI)
- African Americans (ASW) have a similar (but weaker) edge from West Eurasians
- Maasai (MKK) have an even weaker edge from what appears to be a southern Caucasoid population (represented here by Tuscans TSI)
- Gujarati Indians (GIH) are intermediate between East Asians and Europeans, and also have input from a West Eurasian-type population.
This seems like a neat tool for exploring human (and canid ;-) population history.
